Skin consultation
THE BEHAP EDIT SKIN QUALITY
Biomodulator
More hydrated skin
with care for early creasing
Address dry skin, texture
and elasticity together
with an injectable HA combining two molecular weights.
Initial course: 2 sessions · about 30 days apart [1]
Programme prices · Ask BEHAPA CLOSER LOOK AT PROFHILO
An animated look at HA, its distribution in the skin and the cells around it.
ENGLISH ON-SCREEN TEXT · 00:44–01:17
01 — UNDERSTANDING PROFHILO
Good skin.
Thoughtful care.
If you want more hydrated skin while addressing early creasing and reduced elasticity, Profhilo offers an approach to these aspects of skin quality together.
Profhilo is an injectable hyaluronic acid, or HA, that combines two molecular weights using NAHYCO® technology. It addresses skin hydration, elasticity and laxity through the concept of Bioremodelling [1, 2]
A Biomodulator affects how skin cells function. With Profhilo, this includes HA’s water-binding properties and laboratory evidence of effects on cells that produce collagen and elastin. [12]
Improve hydration while addressing elasticity, texture and fine lines, for those who want to improve overall skin quality. [1, 2]
A human study measured increased skin hydration and reduced water loss through the skin after Profhilo was given according to the study’s treatment schedule. [3]
Profhilo’s HA formulation has been shown to stimulate collagen and elastin production in cells and skin models, helping to explain its role as a Biomodulator. [12]
02 — FINDING THE RIGHT APPROACH
Start with what you want to address. Restoring volume and improving skin quality have different goals.
Restore volume
Refine contours
Hydration and skin quality
Select a product to explore its formulation, goals and the concerns it addresses.
VOLUME & CONTOUR
Restore volume and refine facial contours
Used to restore volume or define the shape of specific areas, such as the cheeks, chin or lips. The gel is selected to suit each area. [4]
HYDRATION & TEXTURE
Hydration and skin quality
A group of injectable HA products focused on skin quality. Formulations differ, and some also have evidence relating to elasticity, smoothness and fine lines. [5]
BIOMODULATOR & SKIN QUALITY
A Biomodulator for skin quality
An HA product combining two molecular weights using NAHYCO® technology to address skin hydration, elasticity and laxity. [1, 2]
Skin booster describes a group of injectable treatments for skin quality, while Profhilo is a product name. Their goals overlap in several ways. The choice depends on each product’s formulation, gel properties, method of use and supporting evidence, considered in relation to your skin. [1, 5]
03 — WHERE WE FOCUS
Skin quality care can focus on the areas that concern you: the neck, face and forehead. Your doctor assesses your skin and selects an approach suited to each area. [1, 10]
Neck
For neck skin that is becoming dehydrated, developing fine lines or looking creased, considering smoothness, elasticity and skin laxity together. [1, 9]
Dry neck skin · Fine lines · Early creasing
Face
Addresses skin hydration and elasticity, particularly in the cheeks and areas where skin is starting to become lax. The focus is on skin quality in the treated area. [1, 2]
Hydration · Texture · Elasticity
Forehead
The forehead is another area studied for Profhilo’s effects on skin quality and fine lines. Your doctor assesses your skin and selects an approach suited to this area. [10, 11]
Forehead skin · Texture · Fine linesScroll down to move through each area
KNOW THE PRODUCT FAMILY
The Profhilo family includes different products developed for different treatment goals.
04 — THE SCIENCE, SIMPLIFIED
Each 2 ml of Profhilo contains 32 mg of high-molecular-weight HA and 32 mg of low-molecular-weight HA, totalling 64 mg. NAHYCO® technology uses heat to bring the two molecular weights together in a stable form known as Hybrid Cooperative Complexes [1, 3]
HA binds water. Profhilo’s combination of two molecular weights also has evidence of effects on skin cells, which is why it is described as a Biomodulator [12]
Explore its role as a Biomodulator
PROFHILO AS BIOMODULATOR
From HA’s properties
to skin quality care
Select a topic on the graph to explore water binding, water loss through the skin and effects on cell function, with the research behind each property.
Human study
HA helps retain water in the skin, addressing dryness and dehydration. A human study of Profhilo found increased skin hydration when measured with instruments. [1, 3]
A study of Chinese women who received two Profhilo sessions, four weeks apart, found increased skin hydration at the 12-week follow-up. [3]
Human study
Hydration depends on both the water in the skin and the water that evaporates from it. A human study of Profhilo found reduced transepidermal water loss, or TEWL, after treatment. [3]
TEWL stands for Transepidermal Water Loss. It measures the water that evaporates through the skin. In the same study, participants received two Profhilo sessions, four weeks apart, and TEWL was lower at the 12-week follow-up. [3]
Cells and skin models
Collagen helps maintain skin structure, while elastin supports elasticity. Research in cells and skin models found that Profhilo’s HA formulation stimulated production of both proteins, helping to explain its role as a Biomodulator. [12]
05 — STARTING PROFHILO
2 sessions
About
30 days apart
The manufacturer’s initial treatment guidance. Your doctor adapts the plan to your skin and the area being treated. [1]
First session
Discuss what you want to address and the area you are interested in. Your doctor assesses your skin, selects the injection sites and explains how to care for your skin afterwards.
About 30 days after the first session
Review your skin’s response with your doctor and receive your second Profhilo session according to the initial plan.
After the initial course
Follow changes in hydration, texture and elasticity, then consider ongoing care according to your skin’s condition and needs.
THE BEHAP APPROACH
Care beginsEveryone’s skin has different needs. At BEHAP, care begins with a conversation. We want to understand both your concerns and the results you hope for, so we can plan your skin care together.
Start a consultation06 — A FEW GOOD QUESTIONS
Answers to common questions
about Profhilo
Start with your main concern. If you want to restore lost volume or refine contours, a filler suited to that area would be considered. Hydration, texture and elasticity are goals shared by Profhilo and HA skin boosters. The choice depends on each product’s properties and an assessment of your skin. [1, 4, 5]
See the comparisonProfhilo 64 mg/2 ml is used for skin on the face and neck, with additional studies on the forehead. Your doctor selects an approach suited to each area. Evidence for the backs of the hands and body relates to Profhilo Body, a separate product in the same family. [1, 6, 7, 10, 11]
Explore the treatment areasIt may be considered for people who want to address dehydrated skin, reduced elasticity or laxity on the face and neck. A consultation helps clarify whether your main concern is skin quality, volume or facial structure, so the approach can be matched to your needs. [1, 2]
The manufacturer recommends an initial course of 2 sessions, 30 days apart. Your doctor considers the plan that suits your skin. Ongoing care is then assessed according to your response and individual needs. [1]
Your skin is reviewed at intervals after treatment and again after the initial course. Clinical studies have assessed skin quality at several time points, such as weeks 4, 8, 12 and 16. Plan follow-up with your doctor around the changes you want to assess. [2]
Contact the BEHAP team for programme prices, the number of sessions and what is included. Let us know the area you are interested in and your goals.
Ask about the programme and pricesYou can read BEHAP’s Profhilo aftercare guidance alongside the instructions provided by your medical team after treatment.
Read the aftercare guidanceLET’S TALK ABOUT YOUR SKIN
Ask about Profhilo as a Biomodulator.
Tell us the area you have in mind for pricing details and a consultation appointment.
PROFHILO AT BEHAP
Profhilo consultations are available at both Bangna and Asoke. Tell us the area you want to address and your preferred branch, and the BEHAP team will help arrange your appointment.
BEHAP Bangna · Cascade Bangna
Profhilo is available at our Bangna branch, near Suvarnabhumi Airport.
14/43 Cascade Bangna, Bangna–Trad Road, Bang Kaeo, Bang Phli, Samut Prakan 10540
Call 092 391 9466BEHAP Asoke · Jasmine Building
Profhilo is available at our Asoke branch.
B1, Jasmine Building, Soi Sukhumvit 23, Khlong Toei Nuea, Watthana, Bangkok 10110
Call 096 549 4693Programme information by BEHAP Wellness Clinic · Supporting sources below
Animal study
The inflammatory response is another area of research. In a mouse model of dermatitis, the Profhilo group had lower dermatitis severity scores than the saline group, as well as fewer inflammatory cells in the skin. [13]